Medical Research

Controversial Statistical Issues in Clinical Trials (Chapman by Shein-Chung Chow

By Shein-Chung Chow

In medical trial perform, debatable statistical concerns unavoidably ensue whatever the compliance with sturdy statistical perform and strong scientific perform. yet via choosing the reasons of the problems and correcting them, the learn goals of scientific trials may be larger completed. Controversial Statistical concerns in scientific Trials covers typically encountered arguable statistical matters in medical trials and, every time attainable, makes ideas to unravel those problems.

The ebook makes a speciality of matters taking place at a variety of phases of scientific learn and improvement, together with early-phase scientific improvement (such as bioavailability/bioequivalence), bench-to-bedside translational study, and late-phase medical improvement. a number of examples illustrate the impression of those concerns at the assessment of the protection and efficacy of the try remedy less than research. the writer additionally deals techniques relating to attainable resolutions of the problems.

Written by means of one of many preeminent specialists within the box, this ebook offers an invaluable table reference and state-of-the paintings exam of frustrating matters in medical trials for scientists within the pharmaceutical undefined, medical/statistical reviewers in executive regulatory corporations, and researchers and scholars in academia.

Show description

Read or Download Controversial Statistical Issues in Clinical Trials (Chapman & Hall/CRC Biostatistics Series) PDF

Similar medical research books

Total R & D Management: Strategies and Tactics for 21st Century Healthcare Manufacturers

Drawing on a life of event, Roger Dobbah offers readers an in-depth view of R&D survival innovations and strategies and demonstrates the way to practice them to any association. the writer offers insights into the position of R&D, the the most important subject of creativity and innovation, and the variations and similarities among normal administration and R&D administration.

Basiswissen Medizinische Statistik (Springer-Lehrbuch) (German Edition)

In sixteen Lerneinheiten sicher zur Prüfung. Sämtliche Inhalte sind auf das Wesentliche reduziert und verständlich erklärt – von den Grundlagen bis hin zur Doktorarbeit, von Häufigkeiten bis hin zu Diagnostik-Studien. Ausführliche Rechenbeispiele, "Merke-Boxen" und Herleitungen zeigen Ihnen, wie Sie die Medizinische Statistik anwenden und Ergebnisse aus Studien und Untersuchungen überprüfen.

Statistical Analysis of Clinical Data on a Pocket Calculator, Part 2: Statistics on a Pocket Calculator, Part 2: 0 (SpringerBriefs in Statistics)

The 1st a part of this name contained all statistical checks correct to beginning medical investigations, and incorporated assessments for non-stop and binary info, energy, pattern dimension, a number of trying out, variability, confounding, interplay, and reliability. the present half 2 of this name experiences tools for dealing with lacking info, manipulated facts, a number of confounders, predictions past statement, uncertainty of diagnostic checks, and the issues of outliers.

Advances in Cancer Research: 76

Quantity seventy six of Advances in melanoma examine maintains the sequence' target of publishing well timed and authoritative experiences within the large box of melanoma learn. Ruoslahti starts off the quantity with a assessment of fibronectin and its integrin receptors in melanoma. bankruptcy 2 via Ganter and Lipsick discusses Myb and oncogenesis.

Extra resources for Controversial Statistical Issues in Clinical Trials (Chapman & Hall/CRC Biostatistics Series)

Example text

Download PDF sample

Rated 4.18 of 5 – based on 43 votes